ON THE NOTION OF SYNERGY OF MONOCLONAL ANTIBODIES AS DRUGS
History of developing synergy between monoclonal antibodies, anti-tumor activity of monoclonal antibodies against tyrosine-kinases receptors EGFR/ErbB-1 and HER2/ErbB-2 as well as growth factor VEGF in various combinations are considered in the article.There were proposed hypotheses about potential molecular mechanisms underlay synergy between mono